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目的：评价高聚金葡素在鼻咽癌放射治疗中的作用。方法：１０８例首诊鼻咽癌患者为治疗组，采用高聚金葡素肌肉注射１０００Ｕ，每天一次，联合放射治疗；对照组４８例单纯放射。照射剂量鼻咽部７０～７４Ｇｙ／７～７５ｗ，颈部治疗量约６６Ｇｙ，预防量约５２Ｇｙ。结果：鼻咽部肿块在５０Ｇｙ时和７０Ｇｙ时的消失率治疗组和对照组分别为８６６％、９９１％和３９６％、９５８％，二者经χ２检验差别有显著性（Ｐ＜００１）。治疗全过程中发生白细胞下降治疗组和对照组分别为１８５％和６０４％，差别有显著性（Ｐ＜００５）。治疗中高聚金葡素有轻度发热反应，无其他毒副作用。结论：高聚金葡素与放射治疗联合具有协同、互补和增敏的作用，是一种良好的生物免疫制剂。
OBJECTIVE: To evaluate the role of high-concentration amasechin in radiotherapy of nasopharyngeal carcinoma. Methods: One hundred and eighty patients with nasopharyngeal carcinoma were selected as the treatment group. The mice were injected intramuscularly with 1000U of high-dose a-glucobain once a day for 48 hours. The control group received radiotherapy alone. Radiation dose of nasopharyngeal 70 ~ 74Gy / 7 ~ 7 5w, neck treatment of about 66Gy, prevention of about 52Gy. Results: The disappearance rate of nasopharyngeal mass at 50Gy and 70Gy was 86.6%, 99.1% and 39.6%, 95.8% in the treatment group and the control group respectively. There was a significant difference between the two groups Sex (P <001). The incidence of leukopenia in the whole course of treatment was 18.5% and 60.4% in the treatment group and the control group respectively, with significant difference (P <005). Polygalaectin in the treatment of mild fever, no other side effects. Conclusion: Polygalactin combined with radiotherapy has synergistic, complementary and sensitization effects and is a good bio-immune agent.