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VitK(Vit K_1和Vit K_3)治疗哮喘的机理为:①抑制钙离子流入细胞内;②促使体内cAMP合成;③对抗乙酰胆碱、去甲肾上腺素和组胺对气道平滑肌的作用;①延缓糖皮质素类固醇在肝内的分解。国内学者罗裕绰应用Vit K(Vit K和Vit K_3)治疗80例哮喘.结果总有效率为88.8%.起效时间为:30 min至60 min。陈海兵等应用Vit K_38 mg imi治疗42例哮喘.总有效率为92.9%.im后5~10 min起效。用法:vitK_120~30mg.Vit K_38~16 mg.儿童酌情减量.可选用im、iv。
VitK (Vit K_1 and Vit K_3) treatment of asthma mechanism is: ① inhibit calcium influx into cells; ② promote the synthesis of cAMP; ③ anti-acetylcholine, norepinephrine and histamine on airway smooth muscle; ① delayed glucocorticoid Steroid in liver decomposition. Chinese scholar Luo Yushuo applied Vit K (Vit K and Vit K_3) to treat 80 cases of asthma.Results The total effective rate was 88.8% .The onset time was 30 min to 60 min. Chen Haibing and other applications Vit K_38 mg imi 42 cases of asthma. The total effective rate was 92.9% .im 5 to 10 min onset. Usage: vitK_120 ~ 30mg.Vit K_38 ~ 16 mg. Discretionary children. Optional im, iv.