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目的探讨宁夏汉族女性乳腺癌患者指长波动性不对称(FA)。方法采用体质测量法,分析宁夏汉族女性256例(正常对照128例,乳腺癌患者128例)指长FA(2FA、3FA、4FA、5FA)及复合FA(CFA)的均值,比较其均值的差异性,分析指长FA与年龄间的关系。结果宁夏汉族女性正常对照组与乳腺癌患者组各指长FA均值均呈现2FA>4FA>3FA>5FA的趋势;乳腺癌患者组各指长FA均值均高于对照组,2FA(P<0.01)、4FA、5FA、CFA(P<0.05)差异有显著性,且2FA差异最显著;乳腺癌患者组2FA在|L-R|≥0.04组显著增高(P<0.05);乳腺癌患者组2FA均值与发病年龄呈负相关(P<0.001)。结论 FA,尤其是2FA水平可能是宁夏汉族女性乳腺癌早期筛查的重要间接参考指标之一。
Objective To investigate the long-term fluctuation asymmetry (FA) of Ningxia Han female patients with breast cancer. Methods By means of physical measurement, the mean of FA (2FA, 3FA, 4FA, 5FA) and compound FA (CFA) in 256 Chinese women (128 normal controls and 128 breast cancer patients) Sex, analysis of the relationship between FA and age. Results The mean FA values of normal control and breast cancer patients in Ningxia Han nationality showed the trend of 2FA> 4FA> 3FA> 5FA. The mean FA of each index of breast cancer patients was higher than that of control group (P <0.01) , 4FA, 5FA, CFA (P <0.05), and the difference between 2FA was the most significant. The 2FA level in breast cancer patients was significantly higher than that in LR | ≥0.04 group (P <0.05) Age was negatively correlated (P <0.001). Conclusions FA, especially 2FA, may be one of the important indirect reference markers for early screening of breast cancer in Ningxia Han women.