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目的分析基于目标设置理论的护理干预在植物人颅内电极植入术中的应用效果。方法选取2012年8月至2014年8月间在本院接受治疗的植物生存状态患者30例作为研究对象,均接受颅内电极植入术。根据接受的护理干预措施不同,所有入组患者分为观察组及对照组,每组各15例。对照组患者接受植物人常规护理,观察组患者接受基于目标设置理论的护理干预,随访并记录两组患者的治疗预后、术后并发症发生情况,采用酶联免疫吸附法(ELISA)检测血清神经损伤指标水平。结果 (1)两组患者接受颅内电极植入术后1年内,观察组患者中的死亡比例低于对照组[6.7%(1/15)vs 13.3%(2/15)]、唤醒比例高于对照组[20.0%(3/15)vs 6.7%(1/15)],差异均有统计学意义;(2)观察组患者接受基于目标设置理论的护理干预后,术后颅内出血、脊髓损伤、颅内感染、肺部感染等并发症发生率均明显低于对照组,差异均有统计学意义[0(0/15)vs 13.3%(2/15)、0(0/15)vs 13.3%(2/15)、6.7%(1/15)vs 26.7%(4/15)、13.3%(2/15)vs 40.0%(6/15),P<0.05];(3)观察组患者接受基于目标设置理论的护理干预后,血清神经元特异性烯醇化酶(NSE)、β淀粉样蛋白(Aβ)、星形胶质源性蛋白(S100β)等脑损伤指标水平值均明显低于对照组,差异均有统计学意义[(20.28±4.36)μg/L vs(37.63±6.87)μg/L、(10.92±1.72)μg/L vs(24.31±3.39)μg/L、(0.101±0.018)μg/L vs(0.165±0.027)μg/L,P<0.05]。结论基于目标设置理论的护理干预应用于植物人颅内电极植入术中可以有效优化患者的治疗预后、减少术后并发症发生,保护患者的脑组织免收损伤,具有积极的临床意义。
Objective To analyze the effect of nursing intervention based on target setting theory in intracranial intracranial implantation of human plant. Methods Thirty patients with vegetative state treated in our hospital from August 2012 to August 2014 were enrolled as intracranial electrodes. According to the different nursing interventions, all patients were divided into observation group and control group, 15 cases in each group. Patients in the control group received routine nursing care of patients. The patients in the observation group received nursing intervention based on the theory of target setting. The prognosis and postoperative complications of the two groups were followed up and recorded. Serum nerve injury was detected by enzyme-linked immunosorbent assay (ELISA) Indicator level. Results (1) Within one year after intracranial electrode implantation in both groups, the death rate in the observation group was lower than that in the control group [6.7% (1/15) vs 13.3% (2/15)], and the rate of awakening was high In control group [20.0% (3/15) vs 6.7% (1/15)], the differences were statistically significant; (2) After receiving nursing intervention based on the target setting theory in the observation group, intracranial hemorrhage and spinal cord The incidence of complications such as injury, intracranial infection and pulmonary infection were significantly lower than those in the control group [0 (0/15) vs 13.3% (2/15), 0 (0/15 vs 13.3% (2/15), 6.7% (1/15) vs 26.7% (4/15), 13.3% (2/15) vs 40.0% (6/15), P <0.05] After receiving nursing intervention based on the theory of target setting, the levels of serum neuron specific enolase (NSE), β-amyloid (Aβ) and astrocyte-derived protein (S100β) (20.28 ± 4.36) μg / L vs (37.63 ± 6.87) μg / L, (10.92 ± 1.72) μg / L vs (24.31 ± 3.39) μg / L, (0.101 ± 0.018) μg / L vs (0.165 ± 0.027) μg / L, P <0.05]. Conclusion Nursing intervention based on target setting theory applied in intracranial intracranial implantation of human plant can effectively optimize patient prognosis, reduce postoperative complications and protect patients from brain injury. It has a positive clinical significance.