自青椒(Zanthoxylum schinifolium Sieb.et Zucc.)根分离得到7个化合物,其中2个为新结构定名为青椒内酯(schinifolin I),乙酰氧青椒内酯(acetoxyschinifolin Ⅱ),其他5个为已知化合物,葡萄内酯(aurapten Ⅲ),白鲜碱(dictamnine Ⅳ),滨嵩内酯(scoparoneⅤ),茵芋碱(skimmianine Ⅵ),β-谷甾醇(β-sitosterol Ⅶ)。根据理化性质及光谱数据,Ⅰ,Ⅱ化合物鉴定为7氧代(3′,7′-二甲基-2′,6′-辛二烯)-8-甲氧基香豆素及7氧代(3′,7′-二甲基-5′-乙酰氧基-2′,6′-辛二烯基)8-甲氧基香豆素,化合物Ⅰ、Ⅱ、Ⅲ,Ⅴ在由血小板活化因子(PAF)引起的血小板聚集实验中,具有拮抗血小板聚集的活性。 Seven compounds were isolated from the roots of Zanthoxylum schinifolium Sieb.et Zucc. Two of them were new structures named schinifolin I and acetoxyschinifolin II, and the other five were known Compounds, aurapten III, dictamnine IV, scoparone V, skimmianine VI, and β-sitosterol VII. The compounds Ⅰ and Ⅱ were identified as 7-oxo (3 ’, 7’-dimethyl-2’, 6’-octadiene) -8-methoxycoumarin and 7-oxo (3 ’, 7’-dimethyl-5’-acetoxy-2’, 6’-octadienyl) 8-methoxycoumarin. Compounds I, II, Factor (PAF) induced platelet aggregation experiments, with platelet aggregation antagonistic activity.