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目的：探讨慢性肾衰时残肾组织的演变规律。方法：采用形态计量等方法，动态观察５／６肾切除大鼠残肾形态和功能演变。结果：残肾肾小球毛细血管显著增生、肾单位进行性肥大与毁损并存。结论：残存肾单位的形态代偿与进行性毁损影响和制约着残存肾功能。
Objective: To investigate the evolution of residual renal tissue in patients with chronic renal failure. Methods: Morphometry and other methods were used to dynamically observe the remnant kidney morphology and function of 5/6 nephrectomized rats. Results: Renal glomerular capillary proliferation significantly, nephrotic unit hypertrophy and damage coexist. Conclusion: Morphological compensation and progressive destruction of remnant nephrons affect and restrict the residual renal function.