检测各型乙型肝炎患者血清一氧化氮 (NO) ,谷丙转氨酶 (ALT)和血浆白蛋白 (ALB)含量的变化。收集各型乙型肝炎和肝炎后肝硬化患者及健康者血清作为对照 ,用NO试剂盒检测血清NO浓度 ,实验室常规检测ALT和 (ALB)水平。急性肝炎时 ,血清NO浓度降低 ,ALT升高 ,ALB无明显变化 ,而慢性肝炎、重型肝炎和肝炎后肝硬化患者血清NO和ALB显著升高 ,ALT降低。NO在各型乙肝的发病机制中可能起双重作用。 The levels of serum nitric oxide (NO), alanine aminotransferase (ALT) and plasma albumin (ALB) in patients with various types of hepatitis B were detected. Serum samples from patients with cirrhosis and cirrhosis after hepatitis B and hepatitis B were collected as controls. Serum NO levels were detected with NO kit. ALT and (ALB) levels were routinely measured in the laboratory. In acute hepatitis, serum NO concentration decreased, ALT increased, ALB no significant change, while chronic hepatitis, severe hepatitis and hepatitis cirrhosis patients with serum NO and ALB increased significantly, ALT decreased. NO may play a dual role in the pathogenesis of various types of hepatitis B.