论文部分内容阅读
对54例幽门螺杆菌(HP)根除后患者进行1年以上追踪,定期于停药3,6,12,18,24个月进行~(14)C-尿素呼吸试验检查。呼吸试验阳性者行胃镜复查取胃粘膜活检HP检测证实。结果发现HP感染于停药3个月4例(7±4％),停药6个月1例(1.8％),停药6个月之后无1例。经随机引物DNA多态指模技术鉴定,停药3个月HP感染患者之HP菌株分别与该患者治疗前HP菌株具有相同电泳图谱。结果提示停药早期检出之HP感染实为复发,中国人HP根除后年重感染率不超过2％,与发达国家报道相仿。
54 patients with Helicobacter pylori (HP) were eradicated after more than 1 year follow-up period of 3,6,12,18,24 months on a regular basis to carry out ~ (14) C-urea breath test. Respiratory test positive gastroscopy review gastric biopsy HP test confirmed. HP infection was found in 4 cases (7 ± 4%) in 3 months after discontinuation, 1 case (1.8%) in 6 months after discontinuation, and 1 case after stopping 6 months. The random primer DNA polymorphism fingerprinting identification, HP drug-resistant strains of patients with HP infection after 3 months of withdrawal, respectively, had the same electrophoresis pattern as the HP strain before treatment. The results suggest that early detection of withdrawal HP infection is actually recurrence, the Chinese people after eradication of severe infection rate does not exceed 2%, similar to the developed countries reported.