作者对麻疹-腮腺炎-风疹疫苗(MMR)各种成分的血清阳转率作了比较,并对有无轻型疾病的儿童接种疫苗后不良反应情况进行了评价.1992年2月至1993年4月从亚特兰大市6个接种诊所选择386名15～23月龄儿童作前瞻性调查.收集接种史、最近病史,了解每个儿童的急性疾病症状,并测量体温.在接种前、接种后6～8周分别采集血清作抗体测定.对149名对象,在接种后2周收集接种不良反应的资料.结果表明,386人均作麻疹抗体测定,其 The authors compared the seroconversion rates of various components of the measles-mumps-rubella vaccine (MMR) and evaluated the adverse effects of vaccination in children with or without a mild disease. February 1992-March 1993 4 A total of 386 15- to 23-month-old children from 6 inoculation clinics in Atlanta were selected for prospective investigation in January 2009. Vaccination history, recent medical history, acute illness symptoms of each child and temperature measurements were collected before inoculation, Eight weeks later, serum was collected for antibody assay.Among 149 subjects, information on adverse reactions was collected 2 weeks after inoculation.The results showed that 386 individuals were tested for measles antibody,