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目的 :探索颈动脉狭窄与短暂性脑缺血发作认知功能的相关性。方法 :分析2013年1月~2014年12月在我院被诊断为短暂性脑缺血治疗并伴有颈动脉狭窄患者的临床资料,设为观察组。入院后诊断为单纯短暂性脑缺血的患者纳为对照组。结果 :观察组受试者MMSE、Mo CA、CCSE评分均小于对照组;观察组中、重度患者TIA多次发作的比例较发作一次的比例较高;观察组中TIA伴有颈静脉狭窄的患者N2、P300的潜伏期明显高于对照组患者的潜伏期水平;观察组波幅明显低于对照组。结论 :TIA伴颈动脉狭窄患者的认知能力较单纯TIA患者损害严重,且TIA发作频次越多,血管狭窄程度越重,认知障碍越明显。
Objective: To explore the correlation between carotid artery stenosis and cognitive function of transient ischemic attack. Methods: The clinical data of patients with transient ischemic attack and carotid stenosis who were diagnosed as transient ischemic attack in our hospital from January 2013 to December 2014 were analyzed retrospectively. Patients diagnosed as transient transient ischemic attack admitted to the hospital as control group. Results: The scores of MMSE, Mo CA and CCSE in the observation group were lower than those in the control group. In the observation group, the rate of multiple attacks of TIA was higher in the observation group than in the attacking one. In the observation group, the TIA with jugular vein stenosis N2, P300 latency was significantly higher than the control group patients with latency levels; observation group amplitude was significantly lower than the control group. Conclusion: The cognitive impairment of TIA patients with carotid artery stenosis is more serious than that of TIA patients. The more frequent the TIA is, the more stenosis of blood vessels and the more cognitive impairment.