本实验采用体外细胞培养法评价珊瑚人工骨的细胞相容性。Ｌ９２９小鼠成纤维细胞培养，按细胞增殖度法和形态观察法，取５种浓度珊瑚骨浸提液进行检测，分别于２、４、８、１０天用四唑盐比色法《ＭＴＴ法》计数，计算细胞相对增殖度，用六级毒性分类法评级，分别于２、４天取材扫描电镜观察。结果，培养期细胞大量增殖，形态良好，贴壁生长，毒性评级为０～１级，结果显示珊瑚人工骨具有良好的细胞相容性。 In this study, in vitro cell culture method to evaluate the coherence of coral artificial bone. L929 mouse fibroblasts were cultured according to the method of cell proliferation and morphological observation. Five concentrations of coral bone extract were collected and detected by MTT assay at 2,4,8 and 10 days respectively "Count, calculate the relative proliferation of cells, with six toxic classification rating, respectively, in 2, 4 days by scanning electron microscopy. As a result, the cells proliferated in a large number in the culture period, in good morphology and in adherent growth. The toxicity was graded from 0 to 1 grade. The results showed that the coral artificial bone has good cell compatibility.