Compression creep tests of a Ti-48%Al (mole fraction) alloy were carried out at 1150K with soft-orientated PST crystal. Parallel twinning took placed uring the creep. Changes in lamellar microstructure caused by the parallel twinning were investigated, and their effects on creep deformation behavior were disc ussed. The results show that the parallel twinning occurs in an early stage of creep, and makes significant contribution to creep strain in the domains favorably oriented for the twinning. The nucleation of parallel twins finishes at a strain of about 3%. There is a critical resolved shear stress for parallel twinning, and it is about 50 Mpa in the Ti-48%Al PST crystals at 1150K. The activity of parallel twinning increases with increasing applied stress or in a coarse lamellar mater ial. The addition of parallel twins reduces the average value of lamellar spacin g. In general, the refinement of lamellar structure should improve creep resistance. However the strengthening by parallel twinning is not evident in creep of the soft PST crystals because the soft deformation modes are the dominant deformation mode in the crystals.