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目的探讨声触诊组织定量(VTQ)技术诊断肝脏局灶性病变的临床价值。方法分析163个肝脏局灶性病变,行常规超声记录病灶的位置、长径、短径;应用VTQ技术记录病灶及其周围肝实质的剪切波速度(SWV)。采用ROC曲线评价VTQ技术鉴别良恶性病灶的诊断效能,采用多元线性逐步回归分析方法分析SWV值的影响因素。结果 (1)良恶性病灶间SWV值差异有统计学意义。以SWV=2.25 m/s为诊断界点,其灵敏度为90.1%,特异度为89.3%。(2)多元线性逐步回归分析显示病灶的病理类型是影响SWV的因素;而患者性别、年龄、病灶的位置、深度、长径、短径对SWV值无明显影响。结论 (1)VTQ技术能够较准确的鉴别肝脏良恶性病灶。(2)病灶的病理类型是影响SWV值的主要因素。
Objective To investigate the clinical value of quantitative palpation (VTQ) in the diagnosis of focal liver lesions. Methods Totally 163 liver lesions were analyzed. The location, long diameter and short diameter of lesions were recorded by conventional ultrasound. The shear wave velocity (SWV) of lesions and surrounding liver parenchyma was recorded by VTQ technique. The ROC curve was used to evaluate the diagnostic efficacy of VTQ in distinguishing benign and malignant lesions. The influencing factors of SWV were analyzed by multivariate linear stepwise regression analysis. Results (1) The difference of SWV between benign and malignant lesions was statistically significant. With SWV = 2.25 m / s as the diagnostic endpoint, the sensitivity was 90.1% and the specificity was 89.3%. (2) Multivariate linear stepwise regression analysis showed that the pathological types of the lesions were the factors that affect SWV. However, the gender, age, location of lesions, depth, long diameter and short diameter had no significant effect on SWV. Conclusion (1) VTQ technology can more accurately identify benign and malignant liver lesions. (2) Pathological types of lesions are the main factors affecting the SWV value.