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胃复安是临床常用的止吐药,该药可引发锥体外系症状,自1985~1986年间,我们用胃复安治疗胃肠炎患者3例后,发生锥体外系症状。现报道如下。例1男,15岁。因呕吐口服胃复安10毫克,1小时后出现颈部活动困难,头颈向右侧偏斜,张口呼吸、流涎、精神呆滞,停药7小时后症状消失。例2男,8岁。因呕吐口服胃复安5毫克,3小时后又服5毫克。8小时后出现躁动不安、出汗、口齿不清、口角抽动。考虑为胃复安所致,给予东莨菪硷0.2毫克皮下注射,5小时后上述症
Metoclopramide is a commonly used clinical antiemetic drugs, the drug can cause extrapyramidal symptoms, from 1985 to 1986, we use metoclopramide in patients with gastroenteritis in 3 cases, the occurrence of extrapyramidal symptoms. Report as follows now. Example 1 Male, 15 years old. Due to vomiting, oral metoclopramide 10 mg, 1 hour after the neck movement difficulties, head and neck to the right skew, mouth breathing, salivation, mental retardation, withdrawal symptoms disappear after 7 hours. Example 2 male, 8 years old. Due to vomiting stomach metoclopramide 5 mg, 3 hours after serving 5 mg. 8 hours after the restlessness, sweating, slurred speech, mouth twitch. Consider due to metoclopramide, given scopolamine 0.2 mg subcutaneously, 5 hours after the above symptoms