本文系统回顾了1980年以来口服避孕药(OC)对妇女生殖道癌影响的研究报告。宫内膜癌美国妇女宫体癌发病率约为2%,其中95%来源于官内膜。宫内膜癌年发病率30岁妇女为2.7/100 000,65岁为117/100 000即增加40倍。此癌是一雌激素依赖性肿瘤,因缺乏足够量孕激素对抗的雌激素过多所致。一、OC的影响七十年代中期的病例报告提示曾服OC的患宫内膜癌年轻妇女很 This article systematically reviews studies of the effects of oral contraceptives (OCs) on female genital cancer since 1980. Endometrial cancer The incidence of uterine cancer in American women is about 2%, of which 95% comes from the endometrium. The annual incidence of endometrial cancer in 30-year-old women was 2.7 / 100 000, 65 years old 117/100 000 that is 40-fold increase. This cancer is an estrogen-dependent tumor, due to the lack of adequate estrogen to fight progesterone. First, the impact of OC Case reports of the mid-seventies suggest that women with endometrial cancer had served OC is very young women