论文部分内容阅读
目的探讨肿瘤急诊患者死亡原因及其死亡的危险因素。方法采用回顾性分析方法对2010年1月至12月收治所有986例肿瘤患者进行单因素和多因素Logistic回归分析。结果 986例中男573例(58.1%),女413例(41.9%),年龄中位数为65岁,卡式评分(Karnofsky评分)中位数62分,平均住院日为14 d。死亡124例,住院病死率为12.6%。单因素分析显示,年龄、感染、免疫功能抑制、器官功能衰竭、Karnofsky评分<70分等因素与肿瘤急诊患者死亡有关,具有统计学意义(P<0.05)。多因素Logistic回归分析显示转移部位≥3个(P=0.000,OR 1.920,95.0%CI 1.360～3.618)、器官功能衰竭≥3个(P=0.000,OR 3.252,95.0%CI 1.891～9.363)、KPS<70分(P=0.000,OR 4.462,95.0%CI 2.596～7.762)与肿瘤急诊患者死亡有关。结论转移部位≥3个、器官功能衰竭≥3个、KPS<70分是晚期肿瘤患者死亡的危险因素。
Objective To investigate the causes of death and risk factors of death in patients with cancer emergency. Methods A retrospective analysis was performed on all 986 patients admitted to our hospital from January 2010 to December 2010 with univariate and multivariate Logistic regression analysis. Results Among 986 patients, 573 (58.1%) were male and 413 (41.9%) were female, with a median age of 65 years. The median card score (Karnofsky score) was 62 and the average length of stay was 14 days. 124 deaths, in-hospital mortality was 12.6%. Univariate analysis showed that age, infection, immunosuppression, organ failure, Karnofsky score <70 and other factors related to the death of patients with cancer emergency, with statistical significance (P <0.05). Multivariate Logistic regression analysis showed that the number of metastatic sites was ≥3 (P = 0.000, OR 1.920, 95.0% CI 1.360-3.618), organ failure ≥3 (P = 0.000, OR 3.252, 95.0% CI 1.891-9.363), KPS <70 points (P = 0.000, OR 4.462, 95.0% CI 2.596 ~ 7.762) were related to the death of cancer patients. Conclusions There were ≥3 metastatic sites and ≥3 organ failure. The KPS <70 score was a risk factor for death in advanced cancer patients.