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目的:探讨阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎的临床疗效。方法:回顾性分析我院2013年1月~2014年1月收治的肺炎支原体肺炎患儿80例的临床资料,随机分为对照组和治疗组,对照组在常规治疗的基础上给予红霉素序贯疗法,治疗组在常规治疗的基础上给予阿奇霉素序贯疗法,比较两组的临床疗效、症状或体征消失时间、住院时间及不良反应。结果:治疗组总有效率显著优于对照组,差异有显著性(p<0.05),治疗组退热时间、咳嗽消失时间、肺部啰音消失时间、住院时间均显著低于对照组,差异有显著性(p<0.05),治疗组不良反应发生率显著低于对照组,差异有显著性(p<0.05)。结论:阿奇霉素序贯疗法有助于提高临床疗效,能起到有效的缩短了症状改善的作用,另外还能减轻药物的毒副反应,值得推广。
Objective: To investigate the clinical effect of sequential treatment of azithromycin in children with Mycoplasma pneumoniae pneumonia. Methods: The clinical data of 80 children with Mycoplasma pneumoniae pneumonia admitted from January 2013 to January 2014 in our hospital were retrospectively analyzed. The patients in the control group were randomly divided into control group and treatment group. The control group received erythromycin Sequential therapy, the treatment group was given azithromycin sequential therapy on the basis of routine treatment. The clinical efficacy, disappearance of symptoms or signs, hospital stay and adverse reactions were compared between the two groups. Results: The total effective rate in the treatment group was significantly better than that in the control group (p <0.05). The antipyretic time, the disappearance of cough, the disappearance of pulmonary rales and the length of hospital stay in the treatment group were significantly lower than those in the control group (P <0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (p <0.05). Conclusion: Sequential azithromycin treatment can help to improve the clinical curative effect, can effectively reduce the effect of symptom improvement, and can also reduce the side effects of drugs, which is worth promoting.