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目的探讨布地奈德联合复方异丙托溴铵雾化吸入佐治肺炎支原体肺炎患儿的临床疗效。方法选取2015年10月至2016年10月于抚顺矿务局总医院就诊的100例肺炎支原体感染患儿作为研究对象,随机分为观察组与对照组,各50例。对照组患儿给予氨溴索注射液雾化吸入联合红霉素注射液静脉滴注,观察组患儿在对照组基础上采用布地奈德混悬液联合复方异丙托溴铵雾化吸入。比较两组患儿退热时间、肺部特征消退时间、咳嗽缓解时间、住院时间,并评价两组患儿的疗效。结果观察组患儿退热时间、肺部特征消退时间、咳嗽缓解时间、住院时间均明显短于对照组,差异均有统计学意义(均P<0.05);观察组患儿治疗的总有效率为96.0%,明显高于对照组的74.0%,差异有统计学意义(P<0.05)。结论给予支原体肺炎患儿布地奈德联合复方异丙托溴铵雾化吸入,能及时有效缓解不适症状,发热、咳嗽等症状得到很好控制,住院时间短,减轻了患儿的痛苦。
Objective To investigate the clinical efficacy of budesonide combined with ipratropium bromide in the treatment of children with Mycoplasma pneumoniae pneumonia. Methods A total of 100 children with Mycoplasma pneumoniae infection from October 2015 to October 2016 in the General Hospital of Fushun Mining Bureau were selected as study subjects and randomly divided into observation group and control group with 50 cases each. Patients in the control group were given ambroxol injection aerosol inhalation combined with erythromycin injection intravenously. The patients in the observation group were given budesonide suspension combined with ipratropium bromide inhalation on the basis of the control group. The antipyretic time, the time of lung regression, the time of cough relief, the length of hospital stay and the curative effect of both groups were compared between the two groups. Results The total effective rate of treatment in observation group was significantly lower than that of control group (all P <0.05). The total effective rate of treatment in observation group was significantly lower than that of control group Was 96.0%, which was significantly higher than that of the control group (74.0%), the difference was statistically significant (P <0.05). Conclusion The administration of budesonide combined with ipratropium bromide in children with mycoplasma pneumonia can effectively relieve the symptoms of fever, cough and other symptoms in a timely and effective manner. The hospitalization time is short and the pain of children is alleviated.