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作者报道曾用过蒽环类抗生素治疗的急性非淋巴母细胞白血病(ANLL)复发(12例)和难治的(9例)病人,用阿霉素(60ng/m~2/d)连续治疗3～5天,总有效率为48%,其中复发性ANLL12例中5例和难治性ANLL9例中3例达到完全治愈.其中有1例难治的ANLL病人曾用过大量的蒽环类抗生素(540mg/m~2)和大剂量的阿糖胞苷.本研究证明以前给过阿霉素并不引起对蒽环类抗生素明
The authors report the use of anthracycline-treated acute non-lymphoblastic leukemia (ANLL) recurrences (12 cases) and refractory (9 cases) patients treated with doxorubicin (60 ng / m 2 / d) 3 to 5 days, the total effective rate was 48%, of which 12 cases of recurrent ANLL in 5 cases and 3 cases of refractory ANLL were completely cured of which 1 case of refractory ANLL patients had used a large number of anthracyclines Antibiotics (540mg / m ~ 2) and high doses of cytarabine This study shows that doxorubicin before did not cause anthracycline