目的观察罗格列酮(文迪雅)联合胰岛素强化治疗相对于单独胰岛素强化治疗的疗效。方法将49例2型糖尿病患者随机分成两组,分别给予罗格列酮联合胰岛素强化治疗和单独胰岛素强化治疗,3月后分别测两组患者的血糖情况及胰岛素用量。结果罗格列酮联合组患者的胰岛素使用量低于单独胰岛素强化治疗组,两组患者血糖水平均明显下降,无显著差异。 Objective To observe the effect of rosiglitazone (Avandia) combined with insulin intensive therapy on insulin-alone therapy. Methods Forty-nine patients with type 2 diabetes were randomly divided into two groups. Patients were given rosiglitazone combined with intensive insulin therapy and insulin alone. After three months, blood glucose and insulin dosage were measured in both groups. Results The insulin dosage of rosiglitazone combined group was lower than that of insulin-alone intensive treatment group, and the blood glucose levels of both groups were significantly decreased, with no significant difference.