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目的：探讨控制性肺膨胀（SI）和压力控制（PCV）两种肺复张对肿瘤术后急性呼吸窘迫综合征（ARDS）患者的影响。方法采用随机对照病例研究方法，选择肿瘤术后ARDS患者22例，随机分为SI组和PCV组，每组11例。SI组呼吸机模式改为CPAP模式、压力设为40cmH2O进行机械通气，持续40s。PCV组呼吸机模式改为压力控制，吸气压力（Pressure above PEEP）20cmH2O，I：E=1：1，持续2min。收集2组患者肺复张前、复张后30min、2h、6h各时间点氧合指数（PaO2/FiO2）、静态肺顺应性（Cst）；监测每次肺复张前后血流动力学变化。结果治疗后2组患者PaO2/FiO2、Cst均呈上升趋势（P＜0.01），但在各时间点两组比较差异无统计学意义（P＞0.05）。两组患者在肺复张后心率升高，平均动脉压下降，与复张前比较差异有统计学意义（P＜0.05），PCV组心率和平均动脉压波动幅度低于SI组，差异有统计学意义（P＜0.05）。结论SI与PCV两种肺复张均能改善肺氧合及肺顺应性，PCV肺复张对血流动力学影响低于SI。“,”Objective To investigate the effects of the lung recruitment maneuvers(RMs) with sustained inflation(SI) and pressure control ventilation(PCV) on the acute respiratory distress syndrome(ARDS) for post-operative patients with cancer.Methods 22 ARDS for post-operative patients with cancer were randomized to receive either continuous positive airway pressure(CPAP) of 40cmH2O for 40 seconds(SI group,n=11) or positive-end expiratory pressure of 20cmH2O(I:E=1:1) for 2 minutes(PCV group,n=11).Oxygenation index(PaO2/FiO2) and static pulmonary compliance(Cst) were measured before treatment and at 30min,2h and 6h after treatment. In addition,changes in hemodynamics were monitored before and after RMs.Results The PaO2/FiO2 and Cst signiifcantly increased after treatment in both groups(P0.05).Furthermore,mean arterial pressure decreased and heart rate increased after RMs compared with the values before RMs(P<0.01).Compared with SI group,the amplitude of these parameters significantly decreased in PCV group after RMs(P<0.01).Comclusion RMs with both PCV and SI can increase oxygenation and lung compliance on ARDS for post-operative patients with cancer.Moreover,SI RM has a greater effect than PCV RM on hemodynamics.