对于原发的且病灶局限的胃肠间质瘤(GIST),手术治疗依然是首选的治疗方案。自伊马替尼被用于治疗GIST以来,对于广泛或巨大原发灶,以及复发转移的GIST病人,如何选择手术治疗或靶向药物治疗以及如何把握两者联合治疗,至今仍有争论,尚须进一步探讨。由于伊马替尼对病人的凝血功能可能有影响,对于服药后的GIST病人进行手术治疗时,术中出血量可能较大,所以术前应先停药且纠正凝血功能。 Surgical treatment remains the preferred treatment for primary and localized gastrointestinal stromal tumors (GISTs). Since Imatinib is being used to treat GIST, there is still controversy about how to choose surgical treatment or targeted drug therapy and how to treat the combination of the two, with extensive or large primary tumors and with recurrent GIST. Need to further explore. As imatinib may have an impact on the patient’s coagulation function, bleeding may be large during surgical treatment of the GIST patient after taking the medication, so the medication should be stopped and the coagulation function corrected before surgery.