膀胱输尿管返流(vesicoureteral reflux,VUR),是指尿液自膀胱返流到输尿管。返流性肾病(reflux nephropathy,RN),是指由于尿液进一步返流到肾内导致的肾脏疾病。自1893年Pozzi首次报道人类发生VUR以来,临床上认识到VUR的存在已近一个世纪,直到1950年Hutch证明了返流患者引起肾脏改变,始得到临床医生重视。近三十年来了解到 Vesicoureteral reflux (VUR) refers to the return of urine from the bladder to the ureter. Reflux nephropathy (RN), refers to the kidney due to further reflux of urine into the kidney disease. Since Pozzi first reported human VUR in 1893, it has been clinically recognized that VUR has existed for nearly a century. It was not until 1950 that Hutch proved that renal reflux was caused by reflux in patients, and clinicians should pay attention to it. Learned in nearly thirty years