口服解热镇痛药物引起７ 天以内的新生儿上消化道出血非常少见，我们自１９８９１９９８ 收治４ 例，经及时抢救全部治愈。４ 例患儿均有不合理的服用对胃粘膜有刺激作用的药物史，之后出现呕血、黑便。治疗上均采用了保守治疗，一方面输新鲜血，一方面用止血药如立止血、甲氰咪呱、副肾等、效果满意。文中讨论了致病机制与治疗效果。 Oral antipyretic analgesics caused within 7 days of neonatal upper gastrointestinal bleeding is very rare, we have since 1989  1998, 4 cases were treated, promptly cured all cured. 4 cases of children have unreasonable to take the role of the gastric mucosa stimulation of drug history, followed by hematemesis, melena. Treatment are used conservative treatment, on the one hand lose new blood, on the one hand with hemostatic drugs such as standing blood, cimetidine, vice kidney, the effect is satisfactory. The article discusses the pathogenesis and treatment effect.