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骨髓增生异常综合征(MDS)是多能干细胞水平上的恶性变,导致异常克隆的缓慢增殖和分化障碍为特征的克隆性疾患,部分病例属于急性髓型白血病之早期.目前,其诊断主要依据周围血液和骨髓涂片内的细胞形态学改变。但又缺乏特异性. 根据国内、外近年来的研究,证明骨髓活检组织病理学检查,不仅可提供MDS比涂片更为有益的资料,而且还有助于预测预后.本文旨在对MDS时骨髓活检的研究进展作一介绍。
Myelodysplastic syndrome (MDS) is a malignant change in the level of pluripotent stem cells, leading to clonal disorders characterized by slow proliferation and differentiation disorders of abnormal clones, and some cases are early stages of acute myeloid leukemia. At present, the diagnosis is mainly based on Peripheral blood and bone marrow smear cells within the morphological changes. But lack of specificity.According to the domestic and foreign researches in recent years, it is proved that histopathological examination of bone marrow biopsy can not only provide more useful information of MDS than smear, but also help to predict the prognosis.This paper aims to study the effect of MDS Bone marrow biopsy research to make an introduction.