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目的 探讨非小细胞肺癌标记物 (CYFRA 2 1- 1)对非小细胞肺癌 (NSCLC)胸腔积液的诊断价值。方法 用放免法测定了非小细胞肺癌 ,小细胞肺癌 (SCLC)及结核性胸膜炎的胸腔积液CYFRA 2 1- 1水平。结果 非小细胞肺癌胸腔积液的CYFRA 2 1- 1水平 ,无论细胞学阳性或阴性 ,均显著高于小细胞肺癌及结核性胸膜炎的胸腔积液组 (P <0 0 1)。结论 检测胸腔积液CYFRA 2 1- 1对非小细胞肺癌胸腔积液的诊断有重要价值
Objective To investigate the diagnostic value of non-small cell lung cancer marker (CYFRA 2 1-1) in pleural effusion of non-small cell lung cancer (NSCLC). Methods The level of CYFRA 2 1 - 1 in pleural effusion of non-small cell lung cancer, small cell lung cancer (SCLC) and tuberculous pleurisy was determined by radioimmunoassay. Results The level of CYFRA 2 1 - 1 in pleural effusion of non-small cell lung cancer was significantly higher than that in small cell lung cancer and tuberculous pleurisy (both P <0.01), regardless of whether cytology was positive or negative. Conclusions The detection of pleural effusion CYFRA 2 1-1 has important value in the diagnosis of pleural effusion of non-small cell lung cancer