目的:观察增强CT联合血清糖类抗原在肺癌诊断中的应用效果.方法:随机抽选本院2018年1月-2020年12月间收治的30例肺癌患者(观察组),患者均进行血清糖类抗原水平检测,同时行增强CT检查,对增强CT结合血清糖类抗原检查结果进行分析,选取同期30例肺部良性病变患者作为对照组.结果:CA19-9水平及CA125水平方面,观察组比对照组高;增强CT、CA19-9和CA125肺癌诊断准确率分别是70.00％、46.67％和53.33％.增强CT肺癌诊断准确率是70.00％,增强CT+CA125是90.00％“,”Objective: To observe the effect of enhanced CT combined with serum carbohydrate antigen in the diagnosis of lung cancer. Methods 30 Patients with lung cancer (observation grouP) treated in our hosPital from January 2018 to December 2020 were randomly selected. All Patients underwent serum carbohydrate antigen detection and enhanced CT examination. The results of enhanced CT combined with serum carbohydrate antigen examination were analyzed. 30 Patients with benign lung lesions in the same Period were selected as the control grouP.Results The levels of CA19-9 and CA125 in the observation grouP were higher than those in the control grouP; The diagnostic accuracy of enhanced CT, CA19-9 and CA125 lung cancer were 70.00％, 46.67％ and 53.33％ resPectively. The diagnostic accuracy of enhanced CT was 70.00％, that of enhanced CT + CA125 was 90.00％, that of enhanced CT + CA19-9 was 90.00％, and that of enhanced CT + CA125 + CA19-9 was 96.67％. Conclusion enhanced CT combined with serum carbohydrate antigen has a high diagnostic accuracy in the diagnosis of lung cancer, which is worthy of further adoPtion and Promotion in clinic.