热原反应是临床上常见的一种输液反应,它的临床症状为恶寒、颤栗、高热,严重时可致昏迷、休克,甚至危及生命。 热原本身是微生物的代谢产物,是一种内毒素,其化学成份为脂多糖。这种内毒素是一种极强的致热活性的物质,它作用单核细胞和巨噬细胞等靶细胞,促其释放致热质 Pyrogen is a clinically common infusion reaction, its clinical symptoms of aversion to cold, trembling, fever, severe can cause coma, shock, and even life-threatening. Pyrogen itself is a metabolite of microorganisms, is an endotoxin, the chemical composition of lipopolysaccharide. This endotoxin is an extremely potent pyrogenic substance that acts on target cells such as monocytes and macrophages and promotes its release of pyrogenic