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清解静脉注射液药对小鼠具有抗炎、镇静及镇痛作用,但无抗惊厥作用;对大鼠有消炎作用,能降低家兔对菌苗所致升温反应,且能抑制小鼠体液免疫反应;并能明显降低小鼠血清1gG水平,显著增加小鼠血浆中cAMP及cGMP水平,对肾上腺中Vitc含量都无明显影响;为对血压、呼吸、心率、心电图基本上无变化或有短暂的血压心率下降。急性毒性:皮下注射LD_(50)151.6±0.02g/kg,静脉注射LD_(50)为54.70±0.34g/kg。
Qingjie intravenous drug has anti-inflammatory, sedative and analgesic effects on mice, but no anticonvulsive effects; it has anti-inflammatory effects on rats, can reduce rabbit temperature response to bacterins, and can inhibit mouse body fluids The immune response; and can significantly reduce the mouse serum 1gG levels, significantly increased plasma cAMP and cGMP levels in the adrenal gland, Vitc content had no significant effect; for blood pressure, respiration, heart rate, ECG basically no change or transient The heart rate of the blood pressure drops. Acute toxicity: subcutaneous injection of LD_(50) 151.6±0.02g/kg, intravenous injection of LD_(50) was 54.70±0.34g/kg.