作者报道了11例肝脾型晚期曼氏血吸虫病患者用羟氨喹治疗的结果。患者均为男性农民,12～55岁,脾肿大均超过左肋缘下10cm,并有明显的腹水。用改良加藤氏厚片法检查粪便,连续3天,每克粪的虫卵数为112～2,607个,平均515个。患者于本次治疗前1年内未接受过抗血吸虫药的治疗。10例作了肝组织活检,均为典型的血吸虫性门脉 The authors reported the results of 11 patients treated with hydroxyquramine in patients with late-stage schistosoma mansoni infection of the liver and spleen. Patients were male farmers, 12 to 55 years old, splenomegaly than the left margin of the ribs 10cm, and significant ascites. The faeces were examined with the modified Kato’s thick slice method, and the number of eggs per gram of feces was 112 to 2,607 with an average of 515 for 3 consecutive days. Patients within the 1 year before the treatment did not receive anti-schistosome drug treatment. 10 cases of liver biopsy were made of typical schistosomiasis portal vein