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本文用ELLSA检测,对55例HBV感染者血清中的抗—HBcIgM随访研究其动态变化。结果发现:急性乙肝35例抗—HBcIgM的阳性率在入院时,6个月,12个月分别为100％(35/35),86％(31/36),及 34％(6/18),提示抗—HBcIgM在6个月大都保持阳性,至12个月大部分消失;“无症状”携带者20例抗—HBcIgM阳性率在首检时,6个月,24个月都为100％(各为20/20,17/17,及10/10),提示“无症状”携带者的抗—HBcIgM很难自然消失。同时把抗—HBcIgM和HBsAg检测对比,提示HBsAg阴性不能排除急性乙肝的诊断。
In this paper, ELLSA test, 55 cases of HBV infection in serum anti-HBcIgM follow-up study of its dynamic changes. The results showed that the positive rates of anti-HBcIgM in 35 cases of acute hepatitis B were 100% (35/35), 86% (31/36) and 34% (6/18) respectively at 6 months and 12 months after admission. , Suggesting that anti-HBcIgM mostly remained positive at 6 months, most of them disappeared in 12 months. The positive rate of anti-HBcIgM in 20 patients with “asymptomatic” carriers was 100% at the first 6 months and 24 months, (20/20, 17/17, and 10/10, respectively), suggesting that anti-HBcIgM in “asymptomatic” carriers will hardly naturally disappear. Anti-HBcIgM and HBsAg testing at the same time, suggesting that negative HBsAg can not rule out the diagnosis of acute hepatitis B.