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目的:观察门冬氨酸钾镁对小儿室间隔缺损(VSD) 手术后的抗心律失常及心肌保护作用。方法:先天性VSD 病儿36 例,分为2 组。常规组16例( 男性10 例,女性6 例;年龄7 a±s 4 a) , 术后当日用抗菌药物、强心、利尿及调节酸碱平衡等常规处理;门冬氨酸钾镁组20 例( 男性12 例,女性8 例;年龄7 a±4 a) 术后当天在上述常规治疗基础上加用门冬氨酸钾镁10 ~20 m L, 加入5 % 葡萄糖注射液250 mL, 静脉滴注,qd ,2 组均治疗7 d 。结果:门冬氨酸钾镁组病儿术后心律失常及心肌劳损比常规组较快得到纠正。结论:门冬氨酸钾镁对心脏手术后有抗心律失常及心肌保护作用。
Objective: To observe anti-arrhythmia and myocardial protective effect of potassium magnesium aspartate on pediatric ventricular septal defect (VSD). Methods: Thirty-six children with congenital VSD were divided into two groups. Conventional group of 16 patients (10 males and 6 females; age 7 a ± s 4 a), the day after the use of antimicrobial agents, cardiac, diuretic and regulate acid-base balance conventional treatment; potassium aspartate group 20 (12 males and 8 females; age 7 a ± 4 a). On the day after surgery, 10 to 20 mL potassium magnesium aspartate and 250 mL 5% dextrose injection were intravenously injected on the basis of the above conventional treatment. Instillation, qd, two groups were treated for 7 days. Results: Arrhythmia and myocardial strain in children with potassium-magnesium aspartate group were corrected faster than conventional group. Conclusion: Potassium magnesium aspartate has antiarrhythmic and myocardial protective effects after cardiac surgery.