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目的:探讨阴道镜下行宫颈多点活组织检查对宫颈上皮内瘤样病变(CIN)诊断的准确性。方法:选择2001年1月-2005年12月因CIN行LEEP术者165例,比较阴道镜下行宫颈多点活组织检查与LEEP术后病理检查的结果;探讨阴道镜下多点活组织检查漏诊高级别CIN及宫颈癌的可能影响因素。结果:165例CIN患者宫颈环形电切术与活组织检查术后病理诊断完全符合者103例(62.42%),不符合者62例(37.58%);41例LEEP活组织检查结果比阴道镜下活组织检查结果重(24.85%)。LEEP前诊断为CIN有15例,LEEP术后诊断为浸润癌。结论:阴道镜下行官颈多点活组织检查对CTN的诊断有一定的局限性,对诊断为高级别CIN者,推荐以LEEP除外浸润癌。
Objective: To investigate the accuracy of colposcopic multipoint biopsy in the diagnosis of cervical intraepithelial neoplasia (CIN). Methods: From January 2001 to December 2005, 165 patients underwent CEP with LEEP were retrospectively analyzed. Results of colposcopy biopsy and pathological examination after LEEP were compared. Results of colposcopic multi-point biopsy missed diagnosis High-grade CIN and possible causes of cervical cancer. Results: Totally 103 cases (62.42%) were pathologically diagnosed in 165 cases of CIN and 62 cases (37.58%) did not conform to the pathological diagnosis after biopsy. The results of 41 cases of LEEP biopsy were lower than those of colposcopy Biopsy results were heavy (24.85%). 15 cases were diagnosed as CIN before LEEP, and invasive carcinoma was diagnosed after LEEP. CONCLUSIONS: Colposcopic multipoint biopsy of the cervix has some limitations in the diagnosis of CTN. For patients with high-grade CIN, it is recommended to exclude LEEP in addition to invasive carcinoma.