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目的:观察加味银翘方体外抗甲型流感病毒的作用。方法:以狗肾传代细胞(MDCK)为病毒宿主,测定加味银翘方对甲型流感病毒引起的MDCK病变程度的抑制作用,并设达菲为对照组。结果:在甲型A/粤防/243/72(H3N)2中加味银翘方和对照组达菲的SI分别是4.01和3.86;在甲型A/京防/262/95(H1N)1中加味银翘方和对照组达菲的SI分别是4.40和4.57。结论:加味银翘方对甲型流感病毒所致的MDCK病变有较好的抑制作用,效果与达菲相近。
Objective: To observe the effect of Jiawei Yinqiao Fang on anti-influenza A virus in vitro. Methods: MDCK was used as the virus host to determine the inhibitory effect of Jiawei Yinqiao Recipe on the pathological changes of MDCK induced by influenza A virus. Results: The SI values of Tamiflu and the control group Tamiflu were 4.01 and 3.86 in A / G / 243/72 (H3N) 2, respectively; The SI of Jiawei Yinqiaoqiao and control group Tamiflu was 4.40 and 4.57 respectively. Conclusion: Modified Yinqiao decoction has better inhibitory effect on MDCK caused by influenza A virus, and its effect is similar to that of Tamiflu.