头颈癌的标准治疗方法包括手术和(或)放射治疗,但这类患者的生存率在过去20年内并无改善,Ⅲ、Ⅳ期病例的5年生存率不足50％,多数死于原发癌。化疗虽不是一种根治性措施,但可提高局部区域控制率,减少远处转移和改善生存率。过去几年内已提出多种化疗方案,例如术前化疗(新辅助化疗),与传统治疗同期或之后(辅助)进行化疗。最近在综合治疗中提 The standard treatments for head and neck cancer include surgery and / or radiation therapy. However, the survival rates for these patients have not improved over the past 20 years. The 5-year survival rates for stage III and IV disease are less than 50%, and most die from primary cancer . Although chemotherapy is not a radical measure, it can improve the control rate of local area, reduce the distant metastasis and improve the survival rate. Several chemotherapy regimens have been proposed in the past few years, such as preoperative chemotherapy (neoadjuvant chemotherapy) and concurrent (or adjuvant) chemotherapy with conventional therapy. In the recent comprehensive treatment mentioned