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目的:探讨颈动脉粥样硬化程度和性质特点与脑卒中的关系。方法对14例脑卒中病例(脑出血7例,脑梗塞7例)的颈动脉进行了病理观察及形态定量分析。结果脑梗塞患者的颈动脉粥样硬化程度重于脑出血,尤以颈内动脉表现显著(P<0.05),脑梗塞患者的颈动脉粥样硬化斑块具备不稳定的组织学特性。结论颈动脉狭窄的程度与脑出血或脑梗塞均相关,若粥样硬化块为不稳定状态,则是脑梗塞发病的重要病因。
Objective: To investigate the relationship between carotid atherosclerosis degree and nature and stroke. Methods The carotid arteries of 14 stroke patients (7 with cerebral hemorrhage and 7 with cerebral infarction) were studied by pathology and morphometric analysis. Results The severity of carotid atherosclerosis in patients with cerebral infarction was more severe than that of intracerebral hemorrhage, especially in the internal carotid artery (P <0.05). Carotid atherosclerotic plaques in patients with cerebral infarction had unstable histological features. Conclusion The degree of carotid stenosis is related to cerebral hemorrhage or cerebral infarction. If the atherosclerosis is unstable, it is an important cause of cerebral infarction.