目的 研究普通足月阴道分娩者应用卡前列甲酯栓联合缩宫素对减少产后出血的具体临床疗效?方法 于本院妇产科2021年3月至2021年10月入院待产的足月阴道分娩者中选出160例，随机划分为观察组(采用卡前列甲酯栓联合缩宫素治疗)与对照组(采用缩宫素治疗)， 比较用药后不良反应率?产后宫腔压力变化情况?产后出血量以及血红蛋白下降值?红细胞压积下降值?结果 观察组与对照组产妇产后0.5 h 宫缩强度(51.26±10.22)mm Hg?(50.61±10.17)mm Hg，产后1.0 h 宫缩强度(42.59±1“,”Objective To study the specific clinical efficacy of carboprost methyl ester suppository combined with oxytocin and oxytocin in reducing postpartum hemorrhage. Methods From March 2021 to October 2021， 160 cases of full-term vaginal delivery were selected and randomly divided into observation group (carboprost methyl suppository combined with oxytocin) and control group (oxytocin). The adverse reaction rate after medication， the change of postpartum uterine pressure， the amount of postpartum hemorrhage， the decrease of hemoglobin and hematocrit were analyzed. Results In the observation group and the control group， the uterine contraction intensity at 0.5 h postpartum was (51.26±10.22) mm Hg， (50.61±10.17) mmHg， at 1.0 h postpartum was (42.59±10.54) mm Hg， (40.33±9.84) mm Hg， the amount of bleeding at 2.0 h postpartum was (161.28±12.34) mL， (220.54±27.18) mL， at 24 h postpartum was (180.07±13.94)， (260.27±22.39) mL， and the decrease value of hemoglobin was (0.48±0.03) g/L， (0.81±0.11) g/L， the decrease of hematocrit was (2.97±0.01)%， (5.01±0.02)%， there was significant difference between the two groups (P 0.05). Conclusion Carboprost methyl ester suppository combined with oxytocin has significant curative effect and good safety in reducing postpartum hemorrhage in ordinary full-term vaginal delivery. It can be used as the preferred drug for the prevention of postpartum hemorrhage.