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本文报道颅内转移癌74例(尸检29例,活检45例),占同期颅内肿瘤846例的8.6％。肺癌脑转移最多(50％),这可能与肺的解剖结构有关。转移部位幕上63例(85.1％)以额叶最多(31例);幕下11例(14.9％),以小脑球部为多。颅内病灶尸检组以多发为多(58.6％);外检组以单发为多(80％)。29例死亡材料统计,化疗加支持疗法的16例效果差,平均生存4.4个月,而手术切除13例和(或)放疗、化疗的效果较好,平均生存7.7个月。免疫组化胶原纤维.酸性蛋白(GFA)、S-100蛋白、(S-100)、角蛋白(Keratin)、癌胚抗原(CEA)、对颅内肿瘤的病理诊断、分型及鉴别诊断有重要意义。
This article reports 74 cases of intracranial metastases (autopsy in 29 cases, biopsy 45 cases), accounting for 8.6% of 846 cases of intracranial tumors in the same period. Most brain metastases of lung cancer (50%), which may be related to the anatomy of the lungs. There were 63 cases (85.1%) with frontal lobe metastasis (31 cases), 11 cases (14.9%) with cerebellar bulge. In the intracranial lesions autopsy group was predominantly multiple (58.6%); the external examination group was predominantly single (80%). 29 cases of death material statistics, chemotherapy and supportive treatment of 16 cases of poor results, with an average survival of 4.4 months, while the surgical removal of 13 cases and (or) radiotherapy and chemotherapy, the effect is better, with an average survival of 7.7 months. Immunohistochemical collagen fibers: acidic protein (GFA), S-100 protein, (S-100), keratin, carcinoembryonic antigen (CEA), pathological diagnosis of intracranial tumors, classification and differential diagnosis Significance.