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目的 通过冠状动脉造影和心率变异的测定评价冠状动脉病变与心率变异关系 ,预测冠心病的预后。方法 对 31例冠心病人根据冠状动脉病变程度和部位进行分组与 14名健康人组比较。结果 冠状动脉病变组所有指标 (时域指标SDNN ,SDANN ,RMSSD ,SDNNIndex,PNN50 和频域指标TP ,VLF ,VF ,HF)均明显低于健康组 (P <0 0 5~ 0 0 1)。冠状动脉病变组时域指标降低尤为显著。冠状动脉双支、三支病变和严重狭窄时域指标 (SDNN ,PNN50 % )和频域指标 (LF ,HF)均明显低于病变较轻者 (P <0 0 5~0 0 1)。冠状动脉不同病变部位之间心率变异指标无明显差异。结论 心率变异指标可以反映冠心病的严重程度和预后。
Objective To evaluate the relationship between coronary artery lesions and heart rate variability by measuring coronary angiography and heart rate variability and predict the prognosis of coronary heart disease. Methods 31 cases of coronary heart disease were divided into groups according to the degree and location of coronary lesions compared with 14 healthy people. Results All indexes of coronary artery disease group (SDNN, SDANN, RMSSD, SDNNIndex, PNN50 and frequency domain indicators TP, VLF, VF, HF) were significantly lower than those in healthy group (P <0.05-0.01). Coronary lesions in the time-domain index decreased significantly. The time series of two branches of coronary artery, three lesions and severe stenosis (SDNN, PNN50%) and frequency domain indexes (LF, HF) were significantly lower than those with lesser lesions (P <0.05-0.01). There was no significant difference in heart rate variability between different lesions of coronary artery. Conclusion Heart rate variability index can reflect the severity and prognosis of coronary heart disease.