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聚合物试剂是指具有一定性能的、在聚合物骨架上连接有以共价键相结合的功能基组分的一类反应性高分子物质.从1962年Merrifield把这类试剂用于肽的固相合成以来,发展甚速.近几年来,已广泛地用于多肽、多核苷酸和多糖等的合成,有的已实现了合成过程的自动化.在普通有机合成中,聚合物试剂的应用范围也非常广泛,并可解决一些特殊的合成问题,引起了人们的重视.
Polymer Reagent Refers to a certain performance, the polymer backbone is connected to a covalently bonded functional group component of a class of reactive polymer materials Merrifield from 1962, such reagents for peptide immobilization Phase synthesis has been very rapid development in recent years, has been widely used in the synthesis of peptides, polynucleotides and polysaccharides, and some have realized the automation of the synthesis process.In general organic synthesis, the scope of application of polymer reagents Also very extensive, and can solve some special synthesis problems, aroused people’s attention.