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目的:观察重症急性胰腺炎(SAP)合并早期胰腺感染的易感因素。方法:选取2004年3月～2008年6月间所收治的SAP患者138例,根据发病后2周内胰腺是否继发感染,分为感染组和非感染组,并分析其易感因素。结果:胰腺继发感染的总发生率与低氧血症的有无、胰腺坏死程度、是否手术治疗、肠功能障碍、是否为胆源性胰腺炎以及是否使用呼吸机有明显相关(P<0.05)。结论:胃肠道功能障碍≥5天、低氧血症、胰腺坏死程度、胆源性胰腺炎及手术治疗等是SAP早期胰腺感染的主要易感因素。
Objective: To observe the predisposing factors of severe acute pancreatitis (SAP) complicated with early pancreatic infection. Methods: One hundred and thirty-eight SAP patients were selected from March 2004 to June 2008. According to whether the pancreas was secondary to infection within 2 weeks after the onset of infection, the patients were divided into infected group and non-infected group, and their susceptibility factors were analyzed. RESULTS: The overall incidence of secondary pancreatic infection was significantly related to the presence or absence of hypoxemia, pancreatic necrosis, surgical treatment, bowel dysfunction, whether or not biliary pancreatitis and ventilator use (P <0.05 ). Conclusion: Gastrointestinal dysfunction is more than 5 days, and hypoxemia, pancreatic necrosis, gallstone pancreatitis and surgical treatment are the main susceptible factors of SAP early pancreatic infection.