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目的探讨充血性心力衰竭(congestiveheartfailure,CHF)患者心率变异性(heart rate variability,HRV)变化规律。方法对54例心力衰竭患者进行24小时动态心电图(Holter)监测,然后进行24小时心率变异性分析,将54例心力衰竭患者根据NYHA标准分为心功能Ⅰ~Ⅱ级组27例与心功能Ⅲ~Ⅳ级组27例,比较两组间心率变异性指标变化。同时选取健康对照组29例进行比较。结果心力衰竭组总体标准差(SDNN)、均值标准差(SDANN)、相邻NN间期相差>50ms的个数占总心跳次数的百分比(PNN50)均比健康对照组减低,心功能Ⅰ~Ⅱ级组比心功能Ⅲ~Ⅳ级组SDNN、SDANN、PNN50减低。结论心力衰竭患者心率变异性减低。心功能越差,心率变异性减低越明显。
Objective To investigate the changes of heart rate variability (HRV) in patients with congestive heart failure (CHF). Methods Fifty-four patients with heart failure underwent Holter monitoring 24 hours after heart rate variability analysis. Fifty-four patients with heart failure were divided into two groups according to NYHA criteria: 27 cases of cardiac function Ⅰ ~ Ⅱ group and cardiac function Ⅲ ~ Ⅳ grade group of 27 cases, changes in heart rate variability between the two indicators. At the same time select the healthy control group of 29 patients for comparison. Results The percentage of total standard deviation (SDNN), mean standard deviation (SDANN), difference between adjacent NN intervals> 50 ms in heart failure group and total heart rate (PNN50) were significantly lower than those in healthy controls The level of SDNN, SDANN and PNN50 in patients with grade Ⅲ ~ Ⅳ were lower than those with grade Ⅲ ~ Ⅳ. Conclusions Heart rate variability is reduced in patients with heart failure. The worse heart function, the more obvious decrease of heart rate variability.