在加强看护病人中后死亡的主要原因是伴随着败血症的器官坏死。器官损伤和继发的器官坏死是由下例原因造成的:有毒氧基代谢物释放,各种炎症细胞蛋白酶的释放,免疫复合物的产生,凝结产物的形成。这些物质存在于血管中会导致微血管的栓塞,组织的局部缺血,细胞损伤,最终是器官坏死。在正常情况下,血液中的微废碎片是网状内皮系统的细胞消除的。在动物模型中网状内皮系统的 The main reason for death after intensive care is the necrosis of organs associated with sepsis. Organ damage and secondary organ necrosis are caused by the release of toxic oxygen metabolites, the release of various inflammatory cell proteases, the production of immune complexes, and the formation of coagulation products. The presence of these substances in the blood vessels can lead to embolization of the microvessels, tissue ischemia, cell damage and, ultimately, organ necrosis. Under normal conditions, microfluidic debris in the blood is eliminated by the cells of the reticuloendothelial system. In animal models of reticuloendothelial system