本文报道了19种蛋白质氨基酸的七氟丁酰正丁酯衍生物的GC/MS分析方法;优选了衍生反应条件;建立了GC分离、定量分析方法,最小检测量为0.1ng;研究了衍生物的EI质谱数据,确定了可作为定性依据的特征离子;测定了儿童用复方氨基酸注射液及儿童血清样品,得到了满意的结果。 In this paper, the GC / MS method of 19 heptafluorobutyryl-n-butyl ester derivatives of amino acids was reported. The derivatization conditions were optimized. The method of GC separation and quantitation was established. The minimum detectable amount was 0.1 ng. Of the EI mass spectrometry data to determine the characteristics of ions can be used as a qualitative basis; Determination of children with compound amino acid injection and serum samples of children, and obtained satisfactory results.