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本研究月的是通过器官组织学巨型切片检查来了解喉癌放疗后软骨坏死和/或骨髓炎的发生率及发病部位并确定在其病理发生上的有关重要因素。作者应用全喉连续切片技术共研究265例全喉标小,除2例为尸检标本外,余均为原发性喉癌的全喉手术标本。每个标本按UICC 术后组织病理学分期标准进行分类。49例没接受过放疗,216例为放疗后病例,放疗剂量大多为5500拉德/5周。248例标本于原发部位有癌残留;158例为声门型,78例声门上型,6例声门下型,23例为贯穿型。全组207例为PT 和PT 期喉癌(78%)。41例早期瘤(PT-PT)仅1例(2%)发生放射性坏死,其肿瘤放射量达7000拉德。143例接受过足量放疗(4500-6000拉德)的PT—PT期病人与未接受过放疗的
In this study month, giant organ biopsies were performed to understand the incidence and location of chondrocyte necrosis and/or osteomyelitis after radiotherapy for laryngeal carcinoma and to determine its important pathological factors. The authors used total laryngeal continuous sectioning technique to study 265 cases of total laryngeal sphincter size. Except for 2 cases of autopsy specimens, the rest were all primary laryngeal carcinoma specimens. Each specimen was classified according to the UICC postoperative histopathological staging criteria. Forty-nine patients had not received radiotherapy and 216 were post-radiotherapy. The radiation dose was mostly 5500 rads/5 weeks. 248 specimens had residual cancer at the primary site; 158 were glottis, 78 were supraglottic, 6 were subglottic, and 23 were penetrating. The entire group of 207 patients was PT and PT laryngeal cancer (78%). Radionecrosis occurred in only 1 case (2%) of 41 cases of early tumors (PT-PT), and the tumor had a radiation dose of 7000 rads. 143 patients with PT-PT who have received adequate radiation therapy (4500-6000 rads) and those who have not received radiotherapy