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利多卡因(lidocainum,又名賽罗卡因),由于具有麻醉效力較普魯卡因强、发揮作用快等优点,是最近临床应用較多的一种局部麻醉剂。經动物实驗其毒性与相同浓度的普魯卡因相比:在0.5%溶液时相似,1%溶液較大40%,2%溶液則大50%。临床应用以阻滞麻醉为主,其他如表面麻醉、局部浸潤麻醉等也采用甚广。近年来利多卡因在国內已开始生产,相继有上海、太原、北京等地产品供应。但最近有个別报道根据临床应用的併发症及药检所的鑑定,认为某些产品毒性反应較大。按共鑑定主要
Lidocaine (lidocainum) is a local anesthetic agent with more clinical application recently because of its anesthetic potency and procaine potency. The toxicity of animal experiments compared with the same concentration of procaine: similar in the 0.5% solution, 1% solution larger 40%, 2% solution was 50% larger. Clinical application of anesthesia to block the main others, such as surface anesthesia, local anesthesia is also widely used. In recent years, Lidocaine has started production in China, one after another in Shanghai, Taiyuan, Beijing and other places product supply. However, recently there are several reports based on clinical application of complications and drug testing institute identification, that some products have a greater toxicity. According to the total identification of the main