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虽然早在公元前1500年癌症已为人们所知晓,而且在许多古代医学著作中有用草本植物治疗癌症的记载,但是在1930年以前,用药物来治疗癌症一直未引起人们的重视,直到50年前人们才开始根据癌症患者本身激素状况的变化,应用雄性激素及雌性激素来治疗乳癌、前列腺癌及其他类型的肿瘤。不久以后,由于发现氮芥类和叶酸类似物有抗白血病的作用,因而引起了对癌症化疗剂的认真研究。迄今已有几千种合成的化合物和无数的天然物质已被证实具有生物活性,而且
Although cancer was well known as early as 1500 BC and there is a record that herbs are used to treat cancer in many ancient medical writings, the use of drugs to treat cancer until 1930 has received little attention until 50 years Former people only began to apply androgen and estrogen to treat breast cancer, prostate cancer and other types of cancer according to changes in hormone status in cancer patients. Shortly thereafter, due to the anti-leukemic effects of nitrogen mustards and folic acid analogues, careful study of cancer chemotherapeutics has been initiated. Thousands of synthetic compounds and innumerable natural substances have so far been shown to be biologically active, and