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本文报道了高效液相色谱法分离测定己酮可可减缓释片中有关物质的方法。采用shim-packCLC-OD色谱法,乙腈—0.09%高氯酸溶液(15:85)为流动相,茶苯海明为内标物质,在280nm波长处检测,方法简便、快速,结果准确。
In this paper, a method for the separation and determination of related substances in pentoxifylline sustained-release tablets by high performance liquid chromatography has been reported. Using shim-packCLC-OD chromatography, acetonitrile-0.09% perchloric acid solution (15:85) as the mobile phase, the standard of diphenhydramine as the internal standard was detected at the wavelength of 280 nm. The method was simple, rapid and accurate .