头颈部肿瘤的传统放疗能取得尚可接受的局部控制率,但因对正常组织的毒性限制了进一步提高剂量。口干即为常见的并发症之一。作者研究了调强放疗(IMRT)对头颈部肿瘤提高肿瘤生物有效剂量、同时降低腮腺等正常组织剂量的可能性。 作者报道了4例头颈部肿瘤患者IMRT最优化系统计划的结果,对其中1例作了详细分析,并将其IMRT计划与实际应用的三维适形治疗(3DCRT)计划作比较,另3例仅总结IMRT计划数据。病例1,女,33岁,右软腭粘膜上皮癌,T_4N_0M_0;病例2, Traditional radiotherapy of head and neck cancer can achieve an acceptable local control rate, but toxicity to normal tissues limits further dose increases. Dry mouth is one of the common complications. The authors studied the potential of IMRT to increase the tumor bio-effective dose for head and neck tumors while reducing the dose of parotid and other normal tissues. The authors reported the results of the IMRT Optimization System Plan for 4 patients with head and neck cancer and analyzed one of them in detail and compared their IMRT plan with the actual 3-dimensional conformal treatment (3DCRT) plan. The other 3 patients Summarize IMRT plan data only. Case 1, female, 33 years old, right soft palate mucosa epithelial carcinoma, T_4N_0M_0; Case 2,