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目的:探讨中心静脉导管胸腔置管引流并腔内注入尿激酶治疗结核性包裹性胸腔积液的临床效果。方法:选取本院2012年1月-2015年7月入院治疗的64例结核性包裹性胸腔积液患者作为研究对象。按照治疗方案的不同分为观察组31例与对照组33例,在合理抗结核、对症治疗基础上,观察组患者给予双腔中心静脉导管胸腔置管引流并腔内注入尿激酶治疗,对照组患者给予胸腔穿刺抽取积液治疗。比较两组患者的临床疗效及并发症发生情况。结果:观察组患者的治疗总有效率显著高于对照组,差异具统计学意义(P<0.05)。观察组患者的并发症发生情况少于对照组,差异具统计学意义(P<0.05)。结论:临床应用双腔中心静脉导管胸腔置管引流配合腔内注入尿激酶治疗结核性包裹性胸腔积液,临床疗效确切,并发症少发。
Objective: To investigate the clinical effect of central venous catheter thoracic duct drainage and intrauterine injection of urokinase in the treatment of tuberculous pleural effusion. Methods: A total of 64 patients with tuberculous pleural effusion admitted to our hospital from January 2012 to July 2015 were enrolled in this study. In accordance with the different treatment options were divided into observation group of 31 cases and control group of 33 cases, on the basis of reasonable anti-TB, symptomatic treatment, the observation group was given double-lumen central venous catheter chest catheterization and intra-urokinase infusion treatment, control group Patients given pleural puncture drainage treatment. The clinical efficacy and complications of the two groups were compared. Results: The total effective rate of observation group was significantly higher than that of control group, with statistical significance (P <0.05). The incidence of complications in observation group was less than that in control group, the difference was statistically significant (P <0.05). Conclusion: Clinical application of double-lumen central venous catheter thoracic tube drainage combined with intra-urokinase injection in the treatment of tuberculous pleural effusion, the clinical curative effect, with fewer complications.